Treatment Of Diabetes Is Different For Men And Women

Treatment Of Diabetes Is Different For Men And Women.
Widely hand-me-down diabetes drugs have abundant slang shit on men's and women's hearts, a strange study suggests. Researchers examined how three commonly prescribed treatments for order 2 diabetes affected 78 patients who were divided into three groups. One set took metformin alone, the wink group took metformin with rosiglitazone (sold under the brand name Avandia) and the third troop took metformin plus Lovaza, a type of fish oil found it. Metformin reduces blood sugar assembly by the liver and improves insulin sensitivity.

Rosiglitazone also improves insulin appreciativeness and moves redeem fatty acids out of the blood. Lovaza lowers blood levels of another group of fat called triglycerides. The researchers found that the drugs had very strange and sometimes opposite effects on the hearts of men and women, even as the drugs controlled blood sugar equally well in both genders. The consider appears in the December copy of the American Journal of Physiology - Heart and Circulatory Physiology.

Although metformin had categorical enthusiasm effects in women, it caused the affection metabolism of men to burn less sugar and more fats. Chronic fiery of fat by the heart results in harmful changes that can supervise to heart failure, said the researchers, from the Washington University School of Medicine in St Louis. "Instead of making spirit metabolism more conventional in men, metformin alone made it worse, looking even more get a bang a diabetic heart," study ranking author Dr Robert Gropler said in a university flash release.

And "But in women, metformin had the desired effect - lowering obese metabolism and increasing glucose perceptiveness by the heart". Taking either rosiglitazone or Lovaza with metformin seemed to limit some of the negative heart effects of metformin alone in men. Taking rosiglitazone in joining to metformin further improved women's pity metabolism, compared to taking metformin alone.

The addition of Lovaza to metformin did not have a difficult effect either way for men or women, the researchers said. "Our look suggests that we need to better define which therapies are optimal for women with diabetes and which ones are optimal for men," said Gropler, a professor of radiology. The exploration did not, however, show a cause-and-effect tie-in between the drug combinations and will changes male enhancement solutions. It showed only an association.