Scientists Have Found A New Method Of Cancer Treatment.
Blocking a indication protein convoluted in the advancement of a rare, incurable type of soft-tissue cancer may ice the disease, according to a new study involving mice. Researchers from UT Southwestern found that inhibiting the effectiveness of a protein, known as BRD4, caused cancer cells in virulent peripheral gumption sheath tumors to die fav-store. Malignant peripheral nerve sheath tumors are approvingly aggressive soft-tissue cancers, or sarcomas, that body around nerves.
And "This study identifies a potential untrodden therapeutic target to combat malignant peripheral nerve sheath tumor, an relentless type of cancer that is typically fatal," work senior author Dr Lu Le, an subsidiary professor of dermatology, said in a university news release. "The findings also state important insight into what causes these tumors to develop". The findings were published online Dec 26, 2013 in the paper Cell Reports.
Although invidious peripheral chutzpah sheath tumors can develop randomly, about 50 percent of cases incorporate patients with a genetic disorder called neurofibromatosis species 1. This disorder affects one in 3500 people. About 10 percent of those patients will go on to exploit the soft-tissue cancer, according to the front-page news release. For the study, the researchers examined changes in cells as they evolved into cancerous soft-tissue tumors.
Thursday, April 17, 2014
Friday, April 11, 2014
Doctors Recommend A New Drug For The Prevention Of HIV Infection
Doctors Recommend A New Drug For The Prevention Of HIV Infection.
Should commoners in peril of contracting HIV because they have dicey sex escort a pill to prevent infection, or will the medication encourage them to take even more erotic risks? After years of debate on this question, a new foreign study suggests the medication doesn't lead consumers to stop using condoms or have more sex with more people. The research isn't definitive, and it hasn't changed the heed of every expert vigrxbox.com. But one of the study's co-authors said the findings reinforcement the drug's use as a progress to prevent infection with HIV, the virus that causes AIDS.
And "People may have more partners or stem using condoms, but as well as we can tell, it's not because of taking the drug to baffle HIV infection ," said study co-author Dr Robert Grant, a major investigator with the Gladstone Institute of Virology and Immunology in San Francisco. The medication in dispute is called Truvada, which combines the drugs emtricitabine and tenofovir. It's normally worn to wine and dine people who are infected with HIV, but fact-finding - in gay and bisexual men and in straight couples with one infected accomplice - have shown that it can lower the risk of infection in populace who become exposed to the virus through sex.
However, it does not eliminate the risk of infection. The US Food and Drug Administration approved the poison for avoiding purposes in 2012. Few people seem to be taking it for halt purposes, however. Its manufacturer, Gilead, has disclosed that about 1700 commonality are taking the drug for that reason in the United States, Grant said. In the different study, researchers found that expected rates of HIV and syphilis infection decreased in almost 2500 men and transgender women when they took Truvada.
The haunt participants, who all faced tainted gamble of HIV infection, were recruited in Peru, Ecuador, South Africa, Brazil, Thailand and the United States. Some of the participants took Truvada while others took an supine placebo. Those who believed they were taking Truvada "were just as uninjured as all else," Grant said, suggesting that they weren't more promising to abandon using condoms or be more promiscuous because they believed they had extra protection against HIV infection.
Should commoners in peril of contracting HIV because they have dicey sex escort a pill to prevent infection, or will the medication encourage them to take even more erotic risks? After years of debate on this question, a new foreign study suggests the medication doesn't lead consumers to stop using condoms or have more sex with more people. The research isn't definitive, and it hasn't changed the heed of every expert vigrxbox.com. But one of the study's co-authors said the findings reinforcement the drug's use as a progress to prevent infection with HIV, the virus that causes AIDS.
And "People may have more partners or stem using condoms, but as well as we can tell, it's not because of taking the drug to baffle HIV infection ," said study co-author Dr Robert Grant, a major investigator with the Gladstone Institute of Virology and Immunology in San Francisco. The medication in dispute is called Truvada, which combines the drugs emtricitabine and tenofovir. It's normally worn to wine and dine people who are infected with HIV, but fact-finding - in gay and bisexual men and in straight couples with one infected accomplice - have shown that it can lower the risk of infection in populace who become exposed to the virus through sex.
However, it does not eliminate the risk of infection. The US Food and Drug Administration approved the poison for avoiding purposes in 2012. Few people seem to be taking it for halt purposes, however. Its manufacturer, Gilead, has disclosed that about 1700 commonality are taking the drug for that reason in the United States, Grant said. In the different study, researchers found that expected rates of HIV and syphilis infection decreased in almost 2500 men and transgender women when they took Truvada.
The haunt participants, who all faced tainted gamble of HIV infection, were recruited in Peru, Ecuador, South Africa, Brazil, Thailand and the United States. Some of the participants took Truvada while others took an supine placebo. Those who believed they were taking Truvada "were just as uninjured as all else," Grant said, suggesting that they weren't more promising to abandon using condoms or be more promiscuous because they believed they had extra protection against HIV infection.
Sunday, April 6, 2014
Dangerous Bacteria Live On Chicken Breasts
Dangerous Bacteria Live On Chicken Breasts.
Potentially injurious bacteria was found on 97 percent of chicken breasts bought at stores across the United States and tested, according to a creative sanctum in Dec 2013. And about half of the chicken samples had at least one strain of bacteria that was obstinate to three or more classes of antibiotics, the investigators found disease. The tests on the 316 untested chicken breasts also found that most had bacteria - such as enterococcus and E coli - linked to fecal contamination.
About 17 percent of the E coli were a paradigm that can cause urinary expanse infections, according to the study, published online and in the February 2014 descendant of Consumer Reports. In addition, measure more than 11 percent had two or more types of multidrug-resistant bacteria. Bacteria on the chicken were more unaffected to antibiotics utilized to sponsor chicken growth and to prevent poultry diseases than to other types of antibiotics, the swatting found.
These findings show that "consumers who accept chicken breast at their local grocery stores are very favoured to get a sample that is contaminated and likely to get a bug that is multi-drug resistant. When populate get sick from resistant bacteria, treatment may be getting harder to find," said Dr Urvashi Rangan, a toxicologist and administrative top dog of the Food Safety and Sustainability Center at Consumer Reports. The ammunition has been testing US chicken since 1998, and rates of contamination with salmonella have not changed much during that time, ranging from 11 percent to 16 percent of samples.
Potentially injurious bacteria was found on 97 percent of chicken breasts bought at stores across the United States and tested, according to a creative sanctum in Dec 2013. And about half of the chicken samples had at least one strain of bacteria that was obstinate to three or more classes of antibiotics, the investigators found disease. The tests on the 316 untested chicken breasts also found that most had bacteria - such as enterococcus and E coli - linked to fecal contamination.
About 17 percent of the E coli were a paradigm that can cause urinary expanse infections, according to the study, published online and in the February 2014 descendant of Consumer Reports. In addition, measure more than 11 percent had two or more types of multidrug-resistant bacteria. Bacteria on the chicken were more unaffected to antibiotics utilized to sponsor chicken growth and to prevent poultry diseases than to other types of antibiotics, the swatting found.
These findings show that "consumers who accept chicken breast at their local grocery stores are very favoured to get a sample that is contaminated and likely to get a bug that is multi-drug resistant. When populate get sick from resistant bacteria, treatment may be getting harder to find," said Dr Urvashi Rangan, a toxicologist and administrative top dog of the Food Safety and Sustainability Center at Consumer Reports. The ammunition has been testing US chicken since 1998, and rates of contamination with salmonella have not changed much during that time, ranging from 11 percent to 16 percent of samples.
Tuesday, April 1, 2014
Danger of portable beds
Danger of portable beds.
Caution is required when using pocket bed rails because they put tribe at risk for falling or attractive trapped, the US Food and Drug Administration warns Dec 27, 2013. Portable bed rails weld to a normal, adult-sized bed, often by sliding a bit of the rail under the mattress or by using the baffle for support scriptovore com. People can get trapped in or around the rail, including between the bed-rail bars, between the baluster and the mattress, or between the rail and the headboard, said Joan Todd, a ranking nurse-consultant at the FDA.
And "Consumers distress to realize that even when bed rails are well designed and used correctly, they can distribute a hazard to certain individuals - particularly to occupy with physical limitations or who have an altered mental status, such as dementia or confusion," Todd said in an FDA dispatch release. Between January 2003 and September 2012, the US Consumer Product Safety Commission received reports of 155 deaths and five injuries cognate to pocket-sized bed rails designed for matured use, according to the scoop release.
More than 90 percent of the deaths were caused by entrapment. Of the 155 deaths, 129 occurred in multitude venerable 60 or older and 94 occurred at home. About half of the victims had a medical acclimatize such as enthusiasm disease, Alzheimer's disease or dementia. The FDA has a late website on bed-rail safety that offers information about the latent hazards and advice for safe use.
Caution is required when using pocket bed rails because they put tribe at risk for falling or attractive trapped, the US Food and Drug Administration warns Dec 27, 2013. Portable bed rails weld to a normal, adult-sized bed, often by sliding a bit of the rail under the mattress or by using the baffle for support scriptovore com. People can get trapped in or around the rail, including between the bed-rail bars, between the baluster and the mattress, or between the rail and the headboard, said Joan Todd, a ranking nurse-consultant at the FDA.
And "Consumers distress to realize that even when bed rails are well designed and used correctly, they can distribute a hazard to certain individuals - particularly to occupy with physical limitations or who have an altered mental status, such as dementia or confusion," Todd said in an FDA dispatch release. Between January 2003 and September 2012, the US Consumer Product Safety Commission received reports of 155 deaths and five injuries cognate to pocket-sized bed rails designed for matured use, according to the scoop release.
More than 90 percent of the deaths were caused by entrapment. Of the 155 deaths, 129 occurred in multitude venerable 60 or older and 94 occurred at home. About half of the victims had a medical acclimatize such as enthusiasm disease, Alzheimer's disease or dementia. The FDA has a late website on bed-rail safety that offers information about the latent hazards and advice for safe use.
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