Doctors Recommend A New Treatment For Cancer.
The dope Arimidex reduces the hazard of developing heart cancer by more than 50 percent among postmenopausal women at exalted risk for the disease, according to a new study Dec 2013. The finding, scheduled for production Thursday at the San Antonio Breast Cancer Symposium in Texas, adds wish that Arimidex (anastrozole) might be a valuable young preventive alternative for some women here. The research will also be published in the journal The Lancet.
So "Two other antihormone therapies, tamoxifen and raloxifene, are reach-me-down by some women to enjoin breast cancer, but these drugs are not as effective and can have adverse party effects, which limit their use," study lead prime mover Jack Cuzick said in a new release from the American Association for Cancer Research. "Hopefully, our findings will primacy to an other prevention therapy with fewer side effects for postmenopausal women at squiffed risk for developing breast cancer," said Cuzick, intelligence of the Cancer Research UK Centre for Cancer Prevention and guide of the Wolfson Institute of Preventive Medicine at Queen Mary University of London.
About 80 percent of US teat cancer patients have tumors with dear levels of hormone receptors, and these tumors are fueled by the hormone estrogen. Arimidex prevents the body from making estrogen and is therefore cast-off to expound postmenopausal women with hormone receptor-positive knocker cancer. The study included more than 3800 postmenopausal women at increased danger for breast cancer due to having two or more blood relatives with boob cancer, having a natural or sister who developed breast cancer before time 50, or having a mother or sister who had breast cancer in both breasts.
About half the women took Arimidex for five years while the others took a placebo, or simulation drug. Those who took the cure were 53 percent less suitable to develop breast cancer than those who took the placebo. Side possessions among the women taking the deaden included hot flashes and small increases in muscle aches and pains. The weigh received funding from the opiate companies AstraZeneca and Sanofi-Aventis, and Cuzick is on the speaker's section for AstraZeneca.
Two breast cancer experts in the United States expressed optimism about the unfamiliar findings. "This is very exciting information," said Dr Amy Tiersten, partner professor of cure-all at the Icahn School of Medicine at Mount Sinai, in New York City. She said that although tamoxifen and raloxifene can also nick a woman's unevenness for breast cancer, "these medications can slight increase the risk of blood clots and uterine cancer.
It is great to have a less toxic selection to offer patients in the preventative arena," she said of Arimidex. Dr Stephanie Bernik, leader of surgical oncology at Lenox Hill Hospital in New York City, agreed. "It is with responsive arms that we can go on Arimidex to the medications that can be offered to postmenopausal women that are at excited risk of developing tit cancer.
So "Because Arimidex has less side effects, more women are conceivable to undergo preventive treatment. This will eventually help fall off the incidence of breast cancer in women in this category. We are planning to sustain following the study participants for at least 10 years, and optimistically much longer," study author Cuzick said therapy. "We want to terminate if Arimidex has a continued impact on cancer frequency even after stopping treatment, if it reduces deaths from breast cancer, and to safeguard that there are no long-term adverse side effects".
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