Mammogram warns against cancer.
Often-conflicting results from studies on the value of mechanical mammography have only fueled the argument about how often women should get a mammogram and at what time they should start. In a new division of previous research, experts have applied the same statistical yardstick to four heavy-set studies and re-examined the results. They found that the benefits are more regular across the large studies than previously thought web site. All the studies showed a worthwhile reduction in breast cancer deaths with mammography screening.
So "Women should be reassured that mammography is fully effective," said bone up researcher Robert Smith, senior head of cancer screening for the American Cancer Society. Smith is scheduled to emcee the findings this week at the 2013 San Antonio Breast Cancer Symposium. The findings also were published in the November arise of the gazette Breast Cancer Management.
In 2009, the US Preventive Services Task Force (USPSTF), an unlimited club of national experts, updated its recommendation on mammography, advising women elderly 50 to 74 to get mammograms every two years, not annually.The collect also advised women aged 40 to 49 to balls to their doctors about benefits and harms, and decide on an idiosyncratic basis whether to start screening. Other organizations, including the American Cancer Society, remain to recommend annual screening mammograms beginning at lifetime 40.
In assessing mammography's benefits and harms, researchers often demeanour at the number of women who must be screened to prevent one downfall from breast cancer - a number that has ranged widely amid studies. In assessing harms, experts carry into account the possibility of false positives. Other possible harms allow for finding a cancer that would not otherwise have been found on screening (and not been problematic in a woman's lifetime) and disquiet associated with additional testing.
Smith's gang looked at four large, well-known reviews of the benefit of mammography. These included the Nordic Cochrane review, the UK Independent Breast Screening Review, the USPSTF cavalcade and the European Screening Network review. To homogenize the estimates of how many women privation to be screened to inhibit one breast cancer death, the researchers applied the matter from each of the four reviews to the scenario cast-off in the UK study.
Before this standardized review, the number of women who must be screened to slow one death ranged from 111 to 2000 among the studies. Smith's side found that estimates of the benefits and harms were all based on extraordinary situations. Different age groups were being screened, for instance, and weird follow-up periods were used. Some studies looked at the or slue of women for whom screening is offered and others looked at the tot who actually got mammograms. There often is a huge difference between those two groups.
So "Thirty to 40 percent don't show up, and they are counted as having a mammogram although they did not when they yearn of titty cancer. This hugely depresses the benefits. If you don't have a extensive follow-up, you are not able to accurately melody the benefit. Some women die 20 or more years after the diagnosis". After the researchers old a single, simple scenario, the gap in benefit estimates among studies dropped basically - ranging from 64 to 257 women who must be screened to baffle a single death from breast cancer.
Dr Michael LeFevre, co-vice chairman of the USPSTF, reviewed the uncharted findings but was not confused in the study. "For women aged 50 to 69, it confirms that mammography can minimize deaths from chest cancer. The new analysis doesn't include women in their 40s, which is one of the key parts of the ongoing debate about the use of screening mammography. The job force is in the process of updating the 2009 advice who is also a professor of family and community medicine at the University of Missouri. "The update is not in reaction to the re-analysis vigrx top. It's standard timing for an update".
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