Tamiflu Reduces The Number Of Cases Of Pneumonia In 'Swine Flu' Patients.
When bewitched while after the genesis of symptoms, the antiviral medicament Tamiflu seems to have protected otherwise healthy swine flu patients from contracting pneumonia during the 2009 H1N1 pandemic, Chinese researchers say worldplusmed.net. Tamiflu may also have shortened the aeon that patients were contagious and reduced the duration of their fevers, the check in crew said.
However, reporting in the Sept 29 issuing of 'bmj dot com', the observe authors stressed that their findings should be interpreted with caution given that the conclusions are based on an after-the-fact opinion and on a pool of patients not uniformly given box X-rays at the time of illness. The study team, led by Dr Weizhong Yang and Dr Hongjie Yu from the Chinese Center for Disease Control and Prevention in Beijing, note that in 2009 the fast-spreading influenza A (H1N1) virus killed more than 18000 commonality in over 200 countries.
Monday, March 20, 2017
Friday, March 17, 2017
Stem Cells For Diabetes Treatment
Stem Cells For Diabetes Treatment.
Using an immune-suppressing medication and matured peduncle cells from healthy donors, researchers for example they were able to cure type 1 diabetes in mice. "This is a unimpaired new concept," said the study's older author, Habib Zaghouani, a professor of microbiology and immunology, toddler health and neurology at the University of Missouri School of Medicine in Columbia, Mo. In the mid-point of their laboratory research, something unanticipated occurred how stars grow it. The researchers expected that the mature diminish cells would turn into functioning beta cells (cells that put insulin).
Instead, the stem cells turned into endothelial cells that generated the progress of new blood vessels to fit existing beta cells with the nourishment they needed to regenerate and thrive. "I credence in that beta cells are important, but for curing this disease, we have to fix up the blood vessels ".
It's much too early to cognizant of if this novel combination would work in humans. But the findings could provoke new avenues of research, another expert says. "This is a keynote we've seen a few times recently. Beta cells are ersatz and can respond and expand when the environment is right," said Andrew Rakeman, a chief scientist in beta cell regeneration at the Juvenile Diabetes Research Foundation (JDRF). "But, there's some engender still to be done.
How do we get from this biological physicalism to a more conventional therapy?" Results of the on were published online May 28, 2013 in Diabetes. The claim cause of type 1 diabetes, a chronic virus sometimes called juvenile diabetes, remains unclear. It's cerebration to be an autoimmune disease in which the body's immune organization mistakenly attacks and damages insulin-producing beta cells (found in islet cells in the pancreas) to the dot where they no longer put on insulin, or they produce very little insulin.
Insulin is a hormone necessary to neophyte the carbohydrates from food into fuel for the body and brain. Zaghouani said he thinks the beta cell's blood vessels may just be collateral hurt during the sign autoimmune attack. To avoid dire salubriousness consequences, people with type 1 diabetes must take insulin injections multiple times a time or obtain non-stop infusions through an insulin pump.
Using an immune-suppressing medication and matured peduncle cells from healthy donors, researchers for example they were able to cure type 1 diabetes in mice. "This is a unimpaired new concept," said the study's older author, Habib Zaghouani, a professor of microbiology and immunology, toddler health and neurology at the University of Missouri School of Medicine in Columbia, Mo. In the mid-point of their laboratory research, something unanticipated occurred how stars grow it. The researchers expected that the mature diminish cells would turn into functioning beta cells (cells that put insulin).
Instead, the stem cells turned into endothelial cells that generated the progress of new blood vessels to fit existing beta cells with the nourishment they needed to regenerate and thrive. "I credence in that beta cells are important, but for curing this disease, we have to fix up the blood vessels ".
It's much too early to cognizant of if this novel combination would work in humans. But the findings could provoke new avenues of research, another expert says. "This is a keynote we've seen a few times recently. Beta cells are ersatz and can respond and expand when the environment is right," said Andrew Rakeman, a chief scientist in beta cell regeneration at the Juvenile Diabetes Research Foundation (JDRF). "But, there's some engender still to be done.
How do we get from this biological physicalism to a more conventional therapy?" Results of the on were published online May 28, 2013 in Diabetes. The claim cause of type 1 diabetes, a chronic virus sometimes called juvenile diabetes, remains unclear. It's cerebration to be an autoimmune disease in which the body's immune organization mistakenly attacks and damages insulin-producing beta cells (found in islet cells in the pancreas) to the dot where they no longer put on insulin, or they produce very little insulin.
Insulin is a hormone necessary to neophyte the carbohydrates from food into fuel for the body and brain. Zaghouani said he thinks the beta cell's blood vessels may just be collateral hurt during the sign autoimmune attack. To avoid dire salubriousness consequences, people with type 1 diabetes must take insulin injections multiple times a time or obtain non-stop infusions through an insulin pump.
Thursday, March 16, 2017
Doctors Recommend That Pregnant Women Have To Make A Flu Shot
Doctors Recommend That Pregnant Women Have To Make A Flu Shot.
Pregnant women were urged to get a flu picture during the 2009 H1N1 pandemic, and uncharted proof supports that advice. Norwegian researchers have found that vaccination in pregnancy was safe as houses for look after and child, and that fetal deaths were more tired among unvaccinated moms-to-be. Influenza is a serious foreboding to a pregnant woman and her unborn child, said Dr Camilla Stoltenberg, chief honcho general of the Norwegian Institute of Public Health in Oslo, outrun researcher of the new study vitomol.eu. "Our survey indicates that influenza during pregnancy was a risk factor for stillbirth during the pandemic in 2009".
And "We distinguish no indication that pandemic vaccination in the encourage or third trimester increased the risk of stillbirth". With this year's flu pummeling many citizenry across the United States, experts articulate the best way a pregnant woman can keep safe her unborn baby from flu complications is by getting a flu shot. "In adding to protecting the mother against severe influenza, the vaccine protects the fetus and the toddler in the first months after birth, when the infant is too young to be vaccinated".
The US Centers for Disease Control and Prevention recommends a flu projectile for everyone over 6 months of age. Besides abounding women, the CDC says the grey and anyone with a chronic condition such as asthma or diabetes are especially vulnerable to infection.
For the study, published Jan 16, 2013 in the New England Journal of Medicine, Stoltenberg's group sedate data on more than 117000 women in Norway who were fruitful between 2009 and 2010 - the schedule of the H1N1 pandemic. The investigators found the rate of fetal deaths was almost five per 1000 women.
Pregnant women were urged to get a flu picture during the 2009 H1N1 pandemic, and uncharted proof supports that advice. Norwegian researchers have found that vaccination in pregnancy was safe as houses for look after and child, and that fetal deaths were more tired among unvaccinated moms-to-be. Influenza is a serious foreboding to a pregnant woman and her unborn child, said Dr Camilla Stoltenberg, chief honcho general of the Norwegian Institute of Public Health in Oslo, outrun researcher of the new study vitomol.eu. "Our survey indicates that influenza during pregnancy was a risk factor for stillbirth during the pandemic in 2009".
And "We distinguish no indication that pandemic vaccination in the encourage or third trimester increased the risk of stillbirth". With this year's flu pummeling many citizenry across the United States, experts articulate the best way a pregnant woman can keep safe her unborn baby from flu complications is by getting a flu shot. "In adding to protecting the mother against severe influenza, the vaccine protects the fetus and the toddler in the first months after birth, when the infant is too young to be vaccinated".
The US Centers for Disease Control and Prevention recommends a flu projectile for everyone over 6 months of age. Besides abounding women, the CDC says the grey and anyone with a chronic condition such as asthma or diabetes are especially vulnerable to infection.
For the study, published Jan 16, 2013 in the New England Journal of Medicine, Stoltenberg's group sedate data on more than 117000 women in Norway who were fruitful between 2009 and 2010 - the schedule of the H1N1 pandemic. The investigators found the rate of fetal deaths was almost five per 1000 women.
Treatment Of Oropharyngeal Candidiasis By Oravig (Miconazole) Buccal Tablets
Treatment Of Oropharyngeal Candidiasis By Oravig (Miconazole) Buccal Tablets.
Strativa Pharmaceuticals today announced that the US Food and Drug Administration (FDA) has approved Oravig (miconazole) buccal tablets for the care of oropharyngeal candidiasis (OPC), more commonly known as thrush, in adults and children time 16 and older remedies. Oravig is the beforehand and only local, said preparation formulation of miconazole - an antifungal medication - approved for this use in the US.
Oravig, which adheres to the gum, utilizes innovative buccal tombstone technology enabling once-daily dosing that delivers miconazole entirely at the nearby locale of infection throughout the daytime with minimum systemic absorption. Oravig is easy-to-use and provides patients with a flavorless, odorless and handy treatment option that does not interfere with regularly activities such as eating and drinking.
Oravig will be offered in a 50 mg dosage ability and is expected to be available in retail pharmacies in the third thirteen weeks of 2010. "The FDA approval of Oravig underscores Strativa's commitment to improving patients' overall remedying experience by bringing to peddle new products that fulfill patient needs," said John A MacPhee, President, Strativa Pharmaceuticals. "Oravig offers patients trial from thrush a proven moving healing in a discreet and convenient once-daily formulation".
The FDA confirmation was based on two pivotal Phase III clinical trials. The ahead study demonstrated that Oravig in toto resolved signs and symptoms of OPC at rates similar to Mycelex Troche (clotrimazole) administered five times per era in HIV-positive patients. This randomized, double-blind, double-dummy go was conducted in 577 HIV-positive patients in 28 sites in the United States, Canada, and South Africa. A sec randomized, open-label, multicenter comparative trial run conducted in 282 patients who underwent radiotherapy for control and neck cancer showed that Oravig is non-toxic and operational in this patient population who often has reduced salivary flow.
Strativa Pharmaceuticals today announced that the US Food and Drug Administration (FDA) has approved Oravig (miconazole) buccal tablets for the care of oropharyngeal candidiasis (OPC), more commonly known as thrush, in adults and children time 16 and older remedies. Oravig is the beforehand and only local, said preparation formulation of miconazole - an antifungal medication - approved for this use in the US.
Oravig, which adheres to the gum, utilizes innovative buccal tombstone technology enabling once-daily dosing that delivers miconazole entirely at the nearby locale of infection throughout the daytime with minimum systemic absorption. Oravig is easy-to-use and provides patients with a flavorless, odorless and handy treatment option that does not interfere with regularly activities such as eating and drinking.
Oravig will be offered in a 50 mg dosage ability and is expected to be available in retail pharmacies in the third thirteen weeks of 2010. "The FDA approval of Oravig underscores Strativa's commitment to improving patients' overall remedying experience by bringing to peddle new products that fulfill patient needs," said John A MacPhee, President, Strativa Pharmaceuticals. "Oravig offers patients trial from thrush a proven moving healing in a discreet and convenient once-daily formulation".
The FDA confirmation was based on two pivotal Phase III clinical trials. The ahead study demonstrated that Oravig in toto resolved signs and symptoms of OPC at rates similar to Mycelex Troche (clotrimazole) administered five times per era in HIV-positive patients. This randomized, double-blind, double-dummy go was conducted in 577 HIV-positive patients in 28 sites in the United States, Canada, and South Africa. A sec randomized, open-label, multicenter comparative trial run conducted in 282 patients who underwent radiotherapy for control and neck cancer showed that Oravig is non-toxic and operational in this patient population who often has reduced salivary flow.
Tuesday, March 14, 2017
New Methods Of Treatment Of Ovarian Cancer
New Methods Of Treatment Of Ovarian Cancer.
Women with advanced ovarian cancer who let in fanatical chemotherapy straight away into their stomach area may live at least one year longer than women who inherit standard intravenous chemotherapy, a redone study says. But this survival edge may come at the destruction of more side effects. "The long-term benefits are tuneful significant," said study author Dr Devansu Tewari, commander of gynecologic oncology at the Southern California Permanente Medical Group, in Orange County powder. "There is no look of ovarian cancer treatments that has shown a greater survival advantage".
Intraperitoneal chemotherapy involves bathing the abdominal precinct with chemotherapy agents. By contrast, intravenous (IV) chemotherapy is delivered throughout the body via the bloodstream. The US National Cancer Institute currently recommends intraperitoneal remedy for women with ovarian cancer who have had prominent surgery to exterminate the tumor.
The 10-year backup material from two studies of nearly 900 women with advanced ovarian cancer will be presented Saturday at the annual tryst of the Society of Gynecologic Oncology, in Los Angeles. In 2013, more than 22000 American women will be diagnosed with ovarian cancer, and more than 14000 will be no more from the disease, according to the US National Cancer Institute. There are no primeval screening tests for ovarian cancer, which is why it is often diagnosed when the cancer has already breadth demeanour of the ovaries.
For this reason, survival rates take care of to be very low. In the inexperienced study, women who received the intraperitoneal care were 17 percent more right to survive longer than those who got IV chemotherapy. On average, women in the intraperitoneal rank survived for more than five years, while those who received IV chemotherapy survived for about four years, the learning found. But survival benefits aside, intraperitoneal chemotherapy does converse a greater gamble of side chattels - such as abdominal pain and numbness in the hands and feet - and not all women can admit this high concentration of cancer-killing drugs.
The drugs are also occupied more slowly, providing more exposure to the medicine. The same properties that induce the intraperitoneal therapy more effective likely pit oneself against a role in causing more side effects, the researchers said. In general, six cycles of intraperitoneal chemotherapy are recommended, and can be given in inpatient or outpatient settings. The more cycles the women completed, the greater their survival advantage, the meditate on showed.
Women with advanced ovarian cancer who let in fanatical chemotherapy straight away into their stomach area may live at least one year longer than women who inherit standard intravenous chemotherapy, a redone study says. But this survival edge may come at the destruction of more side effects. "The long-term benefits are tuneful significant," said study author Dr Devansu Tewari, commander of gynecologic oncology at the Southern California Permanente Medical Group, in Orange County powder. "There is no look of ovarian cancer treatments that has shown a greater survival advantage".
Intraperitoneal chemotherapy involves bathing the abdominal precinct with chemotherapy agents. By contrast, intravenous (IV) chemotherapy is delivered throughout the body via the bloodstream. The US National Cancer Institute currently recommends intraperitoneal remedy for women with ovarian cancer who have had prominent surgery to exterminate the tumor.
The 10-year backup material from two studies of nearly 900 women with advanced ovarian cancer will be presented Saturday at the annual tryst of the Society of Gynecologic Oncology, in Los Angeles. In 2013, more than 22000 American women will be diagnosed with ovarian cancer, and more than 14000 will be no more from the disease, according to the US National Cancer Institute. There are no primeval screening tests for ovarian cancer, which is why it is often diagnosed when the cancer has already breadth demeanour of the ovaries.
For this reason, survival rates take care of to be very low. In the inexperienced study, women who received the intraperitoneal care were 17 percent more right to survive longer than those who got IV chemotherapy. On average, women in the intraperitoneal rank survived for more than five years, while those who received IV chemotherapy survived for about four years, the learning found. But survival benefits aside, intraperitoneal chemotherapy does converse a greater gamble of side chattels - such as abdominal pain and numbness in the hands and feet - and not all women can admit this high concentration of cancer-killing drugs.
The drugs are also occupied more slowly, providing more exposure to the medicine. The same properties that induce the intraperitoneal therapy more effective likely pit oneself against a role in causing more side effects, the researchers said. In general, six cycles of intraperitoneal chemotherapy are recommended, and can be given in inpatient or outpatient settings. The more cycles the women completed, the greater their survival advantage, the meditate on showed.
Wednesday, March 8, 2017
People At High Risk Of Alcoholism Also Have More Chances To Suffer From Obesity
People At High Risk Of Alcoholism Also Have More Chances To Suffer From Obesity.
People at higher jeopardize for alcoholism might also right side higher superiority of appropriate obese, new study findings show. Researchers at Washington University School of Medicine in St Louis analyzed text from two substantial US alcoholism surveys conducted in 1991-1992 and 2001-2002. According to the results of the more late-model survey, women with a brood history of alcoholism were 49 percent more seemly to be obese than other women fav-store.net. Men with a strain history of alcoholism were also more likely to be obese, but this association was not as strong in men as in women, said ahead author Richard A Grucza, an helper professor of psychiatry.
One explanation for the increased chance of obesity among people with a family history of alcoholism could be that some public substitute one addiction for another. For example, after a person sees a stifling relative with a drinking problem, they may avoid moonshine but consume high-calorie foods that stimulate the same reward centers in the sense that react to alcohol, Grucza suggested.
In their analysis of the data from both surveys, the researchers found that the tie-in between family history of alcoholism and bulk has grown stronger over time. This may be due to the increasing availability of foods that interact with the same discernment areas as alcohol.
People at higher jeopardize for alcoholism might also right side higher superiority of appropriate obese, new study findings show. Researchers at Washington University School of Medicine in St Louis analyzed text from two substantial US alcoholism surveys conducted in 1991-1992 and 2001-2002. According to the results of the more late-model survey, women with a brood history of alcoholism were 49 percent more seemly to be obese than other women fav-store.net. Men with a strain history of alcoholism were also more likely to be obese, but this association was not as strong in men as in women, said ahead author Richard A Grucza, an helper professor of psychiatry.
One explanation for the increased chance of obesity among people with a family history of alcoholism could be that some public substitute one addiction for another. For example, after a person sees a stifling relative with a drinking problem, they may avoid moonshine but consume high-calorie foods that stimulate the same reward centers in the sense that react to alcohol, Grucza suggested.
In their analysis of the data from both surveys, the researchers found that the tie-in between family history of alcoholism and bulk has grown stronger over time. This may be due to the increasing availability of foods that interact with the same discernment areas as alcohol.
Tuesday, March 7, 2017
Omnitarg And Herceptin Could Save Women Without Chemotherapy From Breast Cancer
Omnitarg And Herceptin Could Save Women Without Chemotherapy From Breast Cancer.
Combinations of targeted therapies for an especially unfriendly standard of core cancer could potentially usher the bulk of affected patients into remission, researchers at a major titty cancer meeting said Friday. Presenting results from three trials at the annual San Antonio Breast Cancer Symposium, scientists explained that administering two or more drugs designed to survey HER2-positive tumors resulted in much higher amnesty rates than doses of any one sedate or column chemotherapy alone retin a for dark spots. Given to patients several weeks before cancer surgery, with or without chemotherapy, the medications often shrank tumors dramatically or eradicated them altogether, the researchers said.
HER2-positive cancer is hospitable to a protein called child epidermal enlargement component receptor 2, which promotes the growth of malignant cells. Drugs that specifically objective HER2 cells - including Herceptin, Tykerb and Omnitarg - have been proven useful on these types of tumors, which cater to to be more aggressive than other breast cancers. "I consider it's a very exciting era, because we've gone from a very lethal time - to a point where we might be able to cure this disease," said Dr Neil Spector, a professor of drug at Duke University Medical Center, who moderated the symposium session.
Using Tykerb and Herceptin combined with chemotherapy before surgery, researchers followed 2,500 women with originally knocker cancer at 85 facilities throughout Germany. About half of these patients achieved deliverance before surgery, said Dr Michael Untch, peak of the multidisciplinary tit cancer subdivision at Helios Clinic in Berlin. "In a majority of these patients, we could do breast-conserving surgery where in the old days they were candidates for mastectomy".
The team will continue following the patients to find out if remission at surgery affects their outcome. Another about showed the combination of Omnitarg and Herceptin, when given with the chemotherapy drug docetaxel, eradicated 46 percent of tumors, 50 percent more than the results achieved without Omnitarg. Also, 17 percent of tumors were eradicated by combining the two targeted drugs and skipping chemotherapy, the researchers said.
Combinations of targeted therapies for an especially unfriendly standard of core cancer could potentially usher the bulk of affected patients into remission, researchers at a major titty cancer meeting said Friday. Presenting results from three trials at the annual San Antonio Breast Cancer Symposium, scientists explained that administering two or more drugs designed to survey HER2-positive tumors resulted in much higher amnesty rates than doses of any one sedate or column chemotherapy alone retin a for dark spots. Given to patients several weeks before cancer surgery, with or without chemotherapy, the medications often shrank tumors dramatically or eradicated them altogether, the researchers said.
HER2-positive cancer is hospitable to a protein called child epidermal enlargement component receptor 2, which promotes the growth of malignant cells. Drugs that specifically objective HER2 cells - including Herceptin, Tykerb and Omnitarg - have been proven useful on these types of tumors, which cater to to be more aggressive than other breast cancers. "I consider it's a very exciting era, because we've gone from a very lethal time - to a point where we might be able to cure this disease," said Dr Neil Spector, a professor of drug at Duke University Medical Center, who moderated the symposium session.
Using Tykerb and Herceptin combined with chemotherapy before surgery, researchers followed 2,500 women with originally knocker cancer at 85 facilities throughout Germany. About half of these patients achieved deliverance before surgery, said Dr Michael Untch, peak of the multidisciplinary tit cancer subdivision at Helios Clinic in Berlin. "In a majority of these patients, we could do breast-conserving surgery where in the old days they were candidates for mastectomy".
The team will continue following the patients to find out if remission at surgery affects their outcome. Another about showed the combination of Omnitarg and Herceptin, when given with the chemotherapy drug docetaxel, eradicated 46 percent of tumors, 50 percent more than the results achieved without Omnitarg. Also, 17 percent of tumors were eradicated by combining the two targeted drugs and skipping chemotherapy, the researchers said.
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